Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymes.

Triosephosphate isomerase (TPI) deficiency is an autosomal recessive disorder caused by various mutations in the gene encoding the key glycolytic enzyme TPI.A drastic decrease in TPI activity and an increased level Headboard Bracket of its substrate, dihydroxyacetone phosphate, have been measured in unpurified cell extracts of affected individuals.

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A case of conjunctival precursor T cell lymphoblastic lymphoma presenting with salmon colored conjunctival mass

Purpose: T-Lymphoblastic lymphoma (T-LBL) is a rare malignant tumor originated from precursor T-lymphocytes that differentiate to T lymphocytes.We report a rare case of T-LBL presenting with conjunctival mass as the first sign.Observations: A 61-year-old man presented with a right salmon colored conjunctival mass.A biopsy was performed, and histopa

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